Protein Tyrosine Phosphatase α Mediates Profibrotic Signaling in Lung Fibroblasts through TGF-β Responsiveness

Fibrotic lung diseases represent a diverse group of progressive and often fatal disorders with limited treatment options. Although the pathogenesis of these conditions remains incompletely understood, receptor type protein tyrosine phosphatase α (PTP-α encoded by PTPRA) has emerged as a key regulato...

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Detalhes bibliográficos
Main Authors: Aschner, Yael, Khalifah, Anthony P., Briones, Natalie, Yamashita, Cory, Dolgonos, Lior, Young, Scott K., Campbell, Megan N., Riches, David W.H., Redente, Elizabeth F., Janssen, William J., Henson, Peter M., Sap, Jan, Vacaresse, Nathalie, Kapus, Andras, McCulloch, Christopher A.G., Zemans, Rachel L., Downey, Gregory P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005983/
https://ncbi.nlm.nih.gov/pubmed/24650563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.01.016
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