Targeting the Mevalonate Cascade as a New Therapeutic Approach in Heart Disease, Cancer and Pulmonary Disease

The cholesterol biosynthesis pathway, also known as the mevalonate (MVA) pathway, is an essential cellular pathway that is involved in diverse cell functions. The enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase (HMGCR) is the rate-limiting step in cholesterol biosynthesis and cataly...

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Detaylı Bibliyografya
Asıl Yazarlar: Yeganeh, Behzad, Wiechec, Emmilia, Ande, Sudharsana R, Sharma, Pawan, Moghadam, Adel Rezaei, Post, Martin, Freed, Darren H., Hashemi, Mohammad, Shojaei, Shahla, Zeki, Amir A., Ghavami, Saeid
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005604/
https://ncbi.nlm.nih.gov/pubmed/24582968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2014.02.007
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