Simvastatin Induces Apoptosis in Medulloblastoma Brain Tumor Cells via Mevalonate Cascade Prenylation Substrates

Medulloblastoma is a common pediatric brain tumor and one of the main types of solid cancers in children below the age of 10. Recently, cholesterol-lowering “statin” drugs have been highlighted for their possible anti-cancer effects. Clinically, statins are reported to have promising potential for c...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Sheikholeslami, Kimia, Ali Sher, Annan, Lockman, Sandhini, Kroft, Daniel, Ganjibakhsh, Meysam, Nejati-Koshki, Kazem, Shojaei, Shahla, Ghavami, Saeid, Rastegar, Mojgan
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678292/
https://ncbi.nlm.nih.gov/pubmed/31319483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11070994
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