Biochemical Characterization of Streptococcus pneumoniae Penicillin-Binding Protein 2b and Its Implication in β-Lactam Resistance

Extensive use of β-lactam antibiotics has led to the selection of pathogenic streptococci resistant to β-lactams due to modifications of the penicillin-binding proteins (PBPs). PBP2b from Streptococcus pneumoniae is a monofunctional (class B) high-molecular-weight PBP catalyzing the transpeptidation...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Pagliero, Estelle, Chesnel, Laurent, Hopkins, Julie, Croizé, Jacques, Dideberg, Otto, Vernet, Thierry, Di Guilmi, Anne Marie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2004
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400559/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15105143/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.5.1848-1855.2004
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