Identification, Purification, and Characterization of Transpeptidase and Glycosyltransferase Domains of Streptococcus pneumoniae Penicillin-Binding Protein 1a

Resistance to β-lactam antibiotics in Streptococcus pneumoniae is due to alteration of penicillin-binding proteins (PBPs). S. pneumoniae PBP 1a belongs to the class A high-molecular-mass PBPs, which harbor transpeptidase (TP) and glycosyltransferase (GT) activities. The GT active site represents a n...

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Main Authors: Di Guilmi, Anne Marie, Mouz, Nicolas, Andrieu, Jean-Pierre, Hoskins, JoAnn, Jaskunas, S. Richard, Gagnon, Jean, Dideberg, Otto, Vernet, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Enzymes and Proteins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC107624/
https://ncbi.nlm.nih.gov/pubmed/9791115
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