The Glycosyltransferase Domain of Penicillin-Binding Protein 2a from Streptococcus pneumoniae Catalyzes the Polymerization of Murein Glycan Chains

The bacterial peptidoglycan consists of glycan chains of repeating β-1,4-linked N-acetylglucosaminyl-N-acetylmuramyl units cross-linked through short peptide chains. The polymerization of the glycans, or glycosyltransfer (GT), and transpeptidation (TP) are catalyzed by bifunctional penicillin-bindin...

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Bibliographic Details
Main Authors: Di Guilmi, Anne Marie, Dessen, Andréa, Dideberg, Otto, Vernet, Thierry
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Enzymes and Proteins
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC165775/
https://ncbi.nlm.nih.gov/pubmed/12867450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.15.4418-4423.2003
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