Identification, Purification, and Characterization of Transpeptidase and Glycosyltransferase Domains of Streptococcus pneumoniae Penicillin-Binding Protein 1a

Resistance to β-lactam antibiotics in Streptococcus pneumoniae is due to alteration of penicillin-binding proteins (PBPs). S. pneumoniae PBP 1a belongs to the class A high-molecular-mass PBPs, which harbor transpeptidase (TP) and glycosyltransferase (GT) activities. The GT active site represents a n...

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Publié dans:	J Bacteriol
Auteurs principaux:	Di Guilmi, Anne Marie, Mouz, Nicolas, Andrieu, Jean-Pierre, Hoskins, JoAnn, Jaskunas, S. Richard, Gagnon, Jean, Dideberg, Otto, Vernet, Thierry
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1998
Sujets:	Enzymes and Proteins
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107624/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9791115/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.21.5652-5659.1998
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