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Identical Penicillin-Binding Domains in Penicillin-Binding Proteins of Streptococcus pneumoniae Clinical Isolates with Different Levels of β-Lactam Resistance

We have sequenced the penicillin-binding domains of the complete repertoire of penicillin-binding proteins and MurM from 22 clinical isolates of Streptococcus pneumoniae that span a wide range of β-lactam resistance levels. Evidence of mosaicism was found in the genes encoding PBP 1a, PBP 2b, PBP 2x...

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Autori principali: Chesnel, Laurent, Carapito, Raphaël, Croizé, Jacques, Dideberg, Otto, Vernet, Thierry, Zapun, André
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168675/
https://ncbi.nlm.nih.gov/pubmed/15980366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.2895-2902.2005
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