Toll-Like Receptor 4–Induced IL-22 Accelerates Kidney Regeneration

AKI involves early Toll-like receptor (TLR)–driven immunopathology, and resolution of inflammation is needed for rapid regeneration of injured tubule cells. Notably, activation of TLRs also has been implicated in epithelial repair. We hypothesized that TLR signaling drives tubule regeneration after...

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Hlavní autoři: Kulkarni, Onkar P., Hartter, Ingo, Mulay, Shrikant R., Hagemann, Jan, Darisipudi, Murthy N., Kumar VR, Santhosh, Romoli, Simone, Thomasova, Dana, Ryu, Mi, Kobold, Sebastian, Anders, Hans-Joachim
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2014
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005301/
https://ncbi.nlm.nih.gov/pubmed/24459235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013050528
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