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Toll-Like Receptor 4–Induced IL-22 Accelerates Kidney Regeneration

AKI involves early Toll-like receptor (TLR)–driven immunopathology, and resolution of inflammation is needed for rapid regeneration of injured tubule cells. Notably, activation of TLRs also has been implicated in epithelial repair. We hypothesized that TLR signaling drives tubule regeneration after...

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Detalhes bibliográficos
Main Authors: Kulkarni, Onkar P., Hartter, Ingo, Mulay, Shrikant R., Hagemann, Jan, Darisipudi, Murthy N., Kumar VR, Santhosh, Romoli, Simone, Thomasova, Dana, Ryu, Mi, Kobold, Sebastian, Anders, Hans-Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005301/
https://ncbi.nlm.nih.gov/pubmed/24459235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013050528
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