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A chemical tool for chemiprecipitation of the lysine methyltransferase, G9a, in vitro and in vivo
Here we report the design, synthesis, and biochemical characterization of a new chemical tool, UNC0965. UNC0965 is a biotinylated version of our previously reported G9a chemical probe, UNC0638. Importantly, UNC0965 maintains high in vitro potency and is cell penetrant. The biotinylated tag of UNC096...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4005005/ https://ncbi.nlm.nih.gov/pubmed/24443078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201300450 |
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