The Two Steps of Poly(A)-Dependent Termination, Pausing and Release, Can Be Uncoupled by Truncation of the RNA Polymerase II Carboxyl-Terminal Repeat Domain

The carboxyl-terminal repeat domain (CTD) of RNA polymerase II is thought to help coordinate events during RNA metabolism. The mammalian CTD consists of 52 imperfectly repeated heptads followed by 10 additional residues at the C terminus. The CTD is required for cleavage and polyadenylation in vitro...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Park, Noh Jin, Tsao, David C., Martinson, Harold G.
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2004
Sujets:	Gene Expression
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400489/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15121832/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.10.4092-4103.2004
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