The Two Steps of Poly(A)-Dependent Termination, Pausing and Release, Can Be Uncoupled by Truncation of the RNA Polymerase II Carboxyl-Terminal Repeat Domain

The carboxyl-terminal repeat domain (CTD) of RNA polymerase II is thought to help coordinate events during RNA metabolism. The mammalian CTD consists of 52 imperfectly repeated heptads followed by 10 additional residues at the C terminus. The CTD is required for cleavage and polyadenylation in vitro...

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Εκδόθηκε σε:	Mol Cell Biol
Κύριοι συγγραφείς:	Park, Noh Jin, Tsao, David C., Martinson, Harold G.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Taylor & Francis 2004
Θέματα:	Gene Expression
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400489/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15121832/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.10.4092-4103.2004
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