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The Two Steps of Poly(A)-Dependent Termination, Pausing and Release, Can Be Uncoupled by Truncation of the RNA Polymerase II Carboxyl-Terminal Repeat Domain

The carboxyl-terminal repeat domain (CTD) of RNA polymerase II is thought to help coordinate events during RNA metabolism. The mammalian CTD consists of 52 imperfectly repeated heptads followed by 10 additional residues at the C terminus. The CTD is required for cleavage and polyadenylation in vitro...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Park, Noh Jin, Tsao, David C., Martinson, Harold G.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400489/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15121832/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.10.4092-4103.2004
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