The Two Steps of Poly(A)-Dependent Termination, Pausing and Release, Can Be Uncoupled by Truncation of the RNA Polymerase II Carboxyl-Terminal Repeat Domain

The carboxyl-terminal repeat domain (CTD) of RNA polymerase II is thought to help coordinate events during RNA metabolism. The mammalian CTD consists of 52 imperfectly repeated heptads followed by 10 additional residues at the C terminus. The CTD is required for cleavage and polyadenylation in vitro...

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Detalhes bibliográficos
Main Authors: Park, Noh Jin, Tsao, David C., Martinson, Harold G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400489/
https://ncbi.nlm.nih.gov/pubmed/15121832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.10.4092-4103.2004
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