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An N-Terminal Truncation Uncouples the Sex-Transforming and Dosage Compensation Functions of Sex-lethal

In Drosophila melanogaster, Sex-lethal (Sxl) controls autoregulation and sexual differentiation by alternative splicing but regulates dosage compensation by translational repression. To elucidate how Sxl functions in splicing and translational regulation, we have ectopically expressed a full-length...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yanowitz, Judith L., Deshpande, Girish, Calhoun, Gretchen, Schedl, Paul D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84096/
https://ncbi.nlm.nih.gov/pubmed/10082569
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