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An N-Terminal Truncation Uncouples the Sex-Transforming and Dosage Compensation Functions of Sex-lethal

In Drosophila melanogaster, Sex-lethal (Sxl) controls autoregulation and sexual differentiation by alternative splicing but regulates dosage compensation by translational repression. To elucidate how Sxl functions in splicing and translational regulation, we have ectopically expressed a full-length...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Yanowitz, Judith L., Deshpande, Girish, Calhoun, Gretchen, Schedl, Paul D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1999
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84096/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082569/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.3018
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