Targeted Disruption of Nrg1 in Granulosa Cells Alters the Temporal Progression of Oocyte Maturation

Neuregulin 1 (NRG1) is induced in granulosa cells by LH and acts on granulosa and cumulus cells during ovulation. In this study, we sought to determine the role of NRG1 in oocyte maturation by generating a granulosa cell–specific Nrg1 knockout mouse (Nrg1(flox/flox);Cyp19a1Cre mice [gcNrg1KO]). In t...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Kawashima, Ikko, Umehara, Takashi, Noma, Noritaka, Kawai, Tomoko, Shitanaka, Manami, Richards, JoAnne S., Shimada, Masayuki
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2014
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004775/
https://ncbi.nlm.nih.gov/pubmed/24650175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1316
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker