Neuregulin 1 Regulates Proliferation of Leydig Cells to Support Spermatogenesis and Sexual Behavior in Adult Mice

Adult Leydig cells are derived from proliferating stem/progenitor Leydig cells in the infant testis and subsequent differentiation to steroidogenic cells in adult mice. Leydig cell proliferation in the infant testis occurs primarily in response to increased levels of LH that induce Leydig cell expre...

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Veröffentlicht in:Endocrinology
Hauptverfasser: Umehara, Takashi, Kawashima, Ikko, Kawai, Tomoko, Hoshino, Yumi, Morohashi, Ken-ichirou, Shima, Yuichi, Zeng, Wenxian, Richards, JoAnne S., Shimada, Masayuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133346/
https://ncbi.nlm.nih.gov/pubmed/27732090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1478
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