The acceleration of reproductive aging in Nrg1 (flox/flox) ;Cyp19‐Cre female mice

Irregular menstrual cycles, reduced responses to exogenous hormonal treatments, and altered endocrine profiles (high FSH/high LH/low AMH) are observed in women with increasing age before menopause. In this study, because the granulosa cell‐specific Nrg1 knockout mice (gcNrg1KO) presented ovarian and...

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Vydáno v:Aging Cell
Hlavní autoři: Umehara, Takashi, Kawai, Tomoko, Kawashima, Ikko, Tanaka, Katsuhiro, Okuda, Satoshi, Kitasaka, Hiroya, Richards, JoAnne S., Shimada, Masayuki
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676068/
https://ncbi.nlm.nih.gov/pubmed/28857490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12662
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