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Creatine enhances the duration of sperm capacitation: a novel factor for improving in vitro fertilization with small numbers of sperm

STUDY QUESTION: Why are many sperm required for successful fertilization of oocytes in vitro, even though fertilization occurs in vivo when only a few sperm reach the oocyte? SUMMARY ANSWER: Creatine produced in the ovary promotes efficient fertilization in vivo; however, in vitro, creatine is not c...

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Detalhes bibliográficos
Publicado no:Hum Reprod
Main Authors: Umehara, Takashi, Kawai, Tomoko, Goto, Masaaki, Richards, JoAnne S, Shimada, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972610/
https://ncbi.nlm.nih.gov/pubmed/29635630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/dey081
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