EGF-Like Factors Induce Expansion of the Cumulus Cell-Oocyte Complexes by Activating Calpain-Mediated Cell Movement

Cumulus cell-oocyte complex (COC) expansion is obligatory for LH-induced ovulation and is initiated by LH induction of the epidermal growth factor (EGF)-like factors that mediate the synthesis of the hyaluronan-rich matrix and hyaluronan-stabilizing factors. COC expansion also involves the movement...

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Bibliographic Details
Main Authors: Kawashima, Ikko, Liu, Zhilin, Mullany, Lisa K., Mihara, Toshihiro, Richards, JoAnne S., Shimada, Masayuki
Format: Artigo
Language:Inglês
Published: Endocrine Society 2012
Subjects:
Reproduction-Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404342/
https://ncbi.nlm.nih.gov/pubmed/22673225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1059
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