CD4-Induced T-20 Binding to Human Immunodeficiency Virus Type 1 gp120 Blocks Interaction with the CXCR4 Coreceptor

The synthetic peptide T-20, which corresponds to a sequence within the C-terminal heptad repeat region (HR2) of the human immunodeficiency virus type 1 (HIV-1) gp41 envelope glycoprotein, potently inhibits viral membrane fusion and entry. Although T-20 is thought to bind the N-terminal heptad repeat...

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書目詳細資料

發表在:	J Virol
Principais autores:	Yuan, Wen, Craig, Stewart, Si, Zhihai, Farzan, Michael, Sodroski, Joseph
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 2004
主題:	Vaccines and Antiviral Agents
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400340/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15113923/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.10.5448-5457.2004
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