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CD4-Induced T-20 Binding to Human Immunodeficiency Virus Type 1 gp120 Blocks Interaction with the CXCR4 Coreceptor

The synthetic peptide T-20, which corresponds to a sequence within the C-terminal heptad repeat region (HR2) of the human immunodeficiency virus type 1 (HIV-1) gp41 envelope glycoprotein, potently inhibits viral membrane fusion and entry. Although T-20 is thought to bind the N-terminal heptad repeat...

詳細記述

保存先:
書誌詳細
出版年:J Virol
主要な著者: Yuan, Wen, Craig, Stewart, Si, Zhihai, Farzan, Michael, Sodroski, Joseph
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400340/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15113923/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.10.5448-5457.2004
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