Cyanovirin-N Binds to gp120 To Interfere with CD4-Dependent Human Immunodeficiency Virus Type 1 Virion Binding, Fusion, and Infectivity but Does Not Affect the CD4 Binding Site on gp120 or Soluble CD4-Induced Conformational Changes in gp120

Cyanovirin-N (CV-N), an 11-kDa protein isolated from the cyanobacterium Nostoc ellipsosporum, potently inactivates diverse strains of human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus. While it has been well established that the viral surface envelope glycoprotein...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Esser, Mark T., Mori, Toshiyuki, Mondor, Isabelle, Sattentau, Quentin J., Dey, Barna, Berger, Edward A., Boyd, Michael R., Lifson, Jeffrey D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Vaccines and Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104217/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10196334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.5.4360-4371.1999
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