Energetics of the HIV gp120-CD4 binding reaction

HIV infection is initiated by the selective interaction between the cellular receptor CD4 and gp120, the external envelope glycoprotein of the virus. We used analytical ultracentrifugation, titration calorimetry, and surface plasmon resonance biosensor analysis to characterize the assembly state, th...

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Autores principales: Myszka, David G., Sweet, Raymond W., Hensley, Preston, Brigham-Burke, Michael, Kwong, Peter D., Hendrickson, Wayne A., Wyatt, Richard, Sodroski, Joseph, Doyle, Michael L.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2000
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC16815/
https://ncbi.nlm.nih.gov/pubmed/10922058
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