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Energetics of the HIV gp120-CD4 binding reaction

HIV infection is initiated by the selective interaction between the cellular receptor CD4 and gp120, the external envelope glycoprotein of the virus. We used analytical ultracentrifugation, titration calorimetry, and surface plasmon resonance biosensor analysis to characterize the assembly state, th...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Myszka, David G., Sweet, Raymond W., Hensley, Preston, Brigham-Burke, Michael, Kwong, Peter D., Hendrickson, Wayne A., Wyatt, Richard, Sodroski, Joseph, Doyle, Michael L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16815/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10922058/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.16.9026
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