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Energetics of the HIV gp120-CD4 binding reaction

HIV infection is initiated by the selective interaction between the cellular receptor CD4 and gp120, the external envelope glycoprotein of the virus. We used analytical ultracentrifugation, titration calorimetry, and surface plasmon resonance biosensor analysis to characterize the assembly state, th...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Myszka, David G., Sweet, Raymond W., Hensley, Preston, Brigham-Burke, Michael, Kwong, Peter D., Hendrickson, Wayne A., Wyatt, Richard, Sodroski, Joseph, Doyle, Michael L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2000
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16815/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10922058/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.16.9026
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