The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions

Research over the last decade has revealed that CYP11A1 can hydroxylate the side chain of vitamin D3 at carbons 17, 20, 22 and 23 to produce at least 10 metabolites, with 20(OH)D3, 20,23(OH)(2)D3, 20,22(OH)(2)D3, 17,20(OH)(2)D3 and 17,20,23(OH)(3)D3 being the main products. However, CYP11A1 does not...

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Bibliografische gegevens
Hoofdauteurs: Slominski, Andrzej T., Kim, Tae-Kang, Li, Wei, Yi, Ae-Kyung, Postlethwaite, Arnold, Tuckey, Robert C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002668/
https://ncbi.nlm.nih.gov/pubmed/24176765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2013.10.012
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