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The role of κ-opioid receptor activation in mediating antinociception and addiction

The κ-opioid receptor (KOR), a member of the opioid receptor family, is widely expressed in the central nervous system and peripheral tissues. Substantial evidence has shown that activation of KOR by agonists and endogenous opioid peptides in vivo may produce a strong analgesic effect that is free f...

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Autors principals: Wang, Yu-hua, Sun, Jian-feng, Tao, Yi-min, Chi, Zhi-qiang, Liu, Jing-gen
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002313/
https://ncbi.nlm.nih.gov/pubmed/20729876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.138
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