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The role of κ-opioid receptor activation in mediating antinociception and addiction
The κ-opioid receptor (KOR), a member of the opioid receptor family, is widely expressed in the central nervous system and peripheral tissues. Substantial evidence has shown that activation of KOR by agonists and endogenous opioid peptides in vivo may produce a strong analgesic effect that is free f...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002313/ https://ncbi.nlm.nih.gov/pubmed/20729876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.138 |
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