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The role of κ-opioid receptor activation in mediating antinociception and addiction

The κ-opioid receptor (KOR), a member of the opioid receptor family, is widely expressed in the central nervous system and peripheral tissues. Substantial evidence has shown that activation of KOR by agonists and endogenous opioid peptides in vivo may produce a strong analgesic effect that is free f...

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Detalhes bibliográficos
Main Authors: Wang, Yu-hua, Sun, Jian-feng, Tao, Yi-min, Chi, Zhi-qiang, Liu, Jing-gen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002313/
https://ncbi.nlm.nih.gov/pubmed/20729876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.138
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