The role of κ-opioid receptor activation in mediating antinociception and addiction

The κ-opioid receptor (KOR), a member of the opioid receptor family, is widely expressed in the central nervous system and peripheral tissues. Substantial evidence has shown that activation of KOR by agonists and endogenous opioid peptides in vivo may produce a strong analgesic effect that is free f...

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Hlavní autoři: Wang, Yu-hua, Sun, Jian-feng, Tao, Yi-min, Chi, Zhi-qiang, Liu, Jing-gen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002313/
https://ncbi.nlm.nih.gov/pubmed/20729876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.138
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