Adenosine A(1) receptor agonist N(6)-cyclohexyl-adenosine induced phosphorylation of delta opioid receptor and desensitization of its signaling

AIM: To define the effect of adenosine A(1) receptor (A(1)R) on delta opioid receptor (DOR)-mediated signal transduction. METHODS: CHO cells stably expressing HA-tagged A(1)R and DOR-CFP fusion protein were used. The localization of receptors was observed using confocal microscope. DOR-mediated inhi...

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Detalhes bibliográficos
Main Authors: Cheng, Yun, Tao, Yi-min, Sun, Jian-feng, Wang, Yu-hua, Xu, Xue-jun, Chen, Jie, Chi, Zhi-qiang, Liu, Jing-gen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007732/
https://ncbi.nlm.nih.gov/pubmed/20562901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.70
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