A carregar...

Agonist Binding and Desensitization of the μ-Opioid Receptor Is Modulated by Phosphorylation of the C-Terminal Tail Domain

Sustained activation of G protein–coupled receptors can lead to a rapid decline in signaling through acute receptor desensitization. In the case of the μ-opioid receptor (MOPr), this desensitization may play a role in the development of analgesic tolerance. It is understood that phosphorylation of M...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Birdsong, William T., Arttamangkul, Seksiri, Bunzow, James R., Williams, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576685/
https://ncbi.nlm.nih.gov/pubmed/25934731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.097527
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!