Paradoxical relationship between RAVE (relative activity versus endocytosis) values of several opioid receptor agonists and their liability to cause dependence

AIM: To examine the relationship between the RAVE (relative activity versus endocytosis) values of opiate agonists and their dependence liability by studying several potent analgesics with special profiles in the development of physical and psychological dependence. METHODS: The effects of (−)-cis-(...

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Main Authors: Wang, Yu-hua, Sun, Jian-feng, Tao, Yi-min, Xu, Xue-jun, Chi, Zhi-qiang, Liu, Jing-gen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007660/
https://ncbi.nlm.nih.gov/pubmed/20228826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.19
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