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Discovery of a retigabine derivative that inhibits KCNQ2 potassium channels
AIM: Retigabine, an activator of KCNQ2-5 channels, is currently used to treat partial-onset seizures. The aim of this study was to explore the possibility that structure modification of retigabine could lead to novel inhibitors of KCNQ2 channels, which were valuable tools for KCNQ channel studies. M...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002159/ https://ncbi.nlm.nih.gov/pubmed/23933653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.79 |
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