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Effect of the KCNQ potassium channel opener retigabine on single KCNQ2/3 channels expressed in CHO cells

KCNQ2/3 potassium channel subunits were co-expressed in Chinese hamster ovary (CHO) cells and currents through single channels recorded using cell-attached patches. Channels had a similar slope conductance in the presence (8.04 ± 0.02 pS) and absence (7.6 ± 0.01 pS) of 10 μm retigabine. The mean max...

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Detalhes bibliográficos
Main Authors: Tatulian, L, Brown, D A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342928/
https://ncbi.nlm.nih.gov/pubmed/12702739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.039842
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