CaMK4-dependent activation of AKT/mTOR and CREM-α underlies autoimmunity-associated Th17 imbalance

Tissue inflammation in several autoimmune diseases, including SLE and MS, has been linked to an imbalance of IL-17–producing Th (Th17) cells and Tregs; however, the factors that promote Th17-driven autoimmunity are unclear. Here, we present evidence that the calcium/calmodulin-dependent protein kina...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Koga, Tomohiro, Hedrich, Christian M., Mizui, Masayuki, Yoshida, Nobuya, Otomo, Kotaro, Lieberman, Linda A., Rauen, Thomas, Crispín, José C., Tsokos, George C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001553/
https://ncbi.nlm.nih.gov/pubmed/24667640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73411
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados