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Cutting Edge: Nanogel-Based Delivery of an Inhibitor of CaMK4 to CD4+ T Cells Suppresses Experimental Autoimmune Encephalomyelitis and Lupus-like Disease in Mice
Treatment of autoimmune diseases is still largely based on the use of systemically acting immunosuppressive drugs, which invariably cause severe side effects. Calcium/calmodulin-dependent protein kinase IV (CaMK4) is involved in the suppression of IL-2 and the production of IL-17. Its pharmacologic...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4670795/ https://ncbi.nlm.nih.gov/pubmed/26561550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501603 |
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