Heme Exporter FLVCR1a Regulates Heme Synthesis and Degradation and Controls Activity of Cytochromes P450

BACKGROUND & AIMS: The liver has one of the highest rates of heme synthesis of any organ. More than 50% of the heme synthesized in the liver is used for synthesis of P450 enzymes, which metabolize exogenous and endogenous compounds that include natural products, hormones, drugs, and carcinogens....

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Main Authors: Vinchi, Francesca, Ingoglia, Giada, Chiabrando, Deborah, Mercurio, Sonia, Turco, Emilia, Silengo, Lorenzo, Altruda, Fiorella, Tolosano, Emanuela
Formato: Artigo
Idioma:Inglês
Publicado: W.B. Saunders 2014
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000440/
https://ncbi.nlm.nih.gov/pubmed/24486949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.01.053
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