Mutations in the Heme Exporter FLVCR1 Cause Sensory Neurodegeneration with Loss of Pain Perception

Pain is necessary to alert us to actual or potential tissue damage. Specialized nerve cells in the body periphery, so called nociceptors, are fundamental to mediate pain perception and humans without pain perception are at permanent risk for injuries, burns and mutilations. Pain insensitivity can be...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Chiabrando, Deborah, Castori, Marco, di Rocco, Maja, Ungelenk, Martin, Gießelmann, Sebastian, Di Capua, Matteo, Madeo, Annalisa, Grammatico, Paola, Bartsch, Sophie, Hübner, Christian A., Altruda, Fiorella, Silengo, Lorenzo, Tolosano, Emanuela, Kurth, Ingo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5140052/
https://ncbi.nlm.nih.gov/pubmed/27923065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006461
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