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Unraveling the Role of Heme in Neurodegeneration
Heme (iron-protoporphyrin IX) is an essential co-factor involved in several biological processes, including neuronal survival and differentiation. Nevertheless, an excess of free-heme promotes oxidative stress and lipid peroxidation, thus leading to cell death. The toxic properties of heme in the br...
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| 出版年: | Front Neurosci |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6189481/ https://ncbi.nlm.nih.gov/pubmed/30356807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00712 |
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