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Unraveling the Role of Heme in Neurodegeneration

Heme (iron-protoporphyrin IX) is an essential co-factor involved in several biological processes, including neuronal survival and differentiation. Nevertheless, an excess of free-heme promotes oxidative stress and lipid peroxidation, thus leading to cell death. The toxic properties of heme in the br...

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Publicat a:Front Neurosci
Autors principals: Chiabrando, Deborah, Fiorito, Veronica, Petrillo, Sara, Tolosano, Emanuela
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189481/
https://ncbi.nlm.nih.gov/pubmed/30356807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00712
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