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Structure-activity Relationships of Peptidomimetics that Inhibit PPI of HER2-HER3

Human epidermal growth factor receptor-2 (HER2) is a tyrosine kinase family protein receptor that is known to undergo heterodimerization with other members of the family of epidermal growth factor receptors (EGFR) for cell signaling. Overexpression of HER2 and deregulation of signaling has implicati...

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Main Authors: Kanthala, Shanthi, Gauthier, Ted, Satyanarayanajois, Seetharama
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998834/
https://ncbi.nlm.nih.gov/pubmed/24222531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22441
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