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Structure-activity relationship of conformationally constrained peptidomimetics for antiproliferative activity in HER2-overexpressing breast cancer cell lines

Human epidermal growth factor receptor 2 (HER2) is a member of the human epidermal growth factor receptor kinases and is involved in a signaling cascade for cell growth and differentiation. It is well established that HER2-mediated heterodimerization has important implications in cancer. Deregulatio...

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Detalhes bibliográficos
Main Authors: Banappagari, Sashikanth, Ronald, Sharon, Satyanarayanajois, Seetharama D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163471/
https://ncbi.nlm.nih.gov/pubmed/21887403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C1MD00126D
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