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A Conformationally Constrained Peptidomimetic Binds to the Extracellular Region of HER2 Protein

Human epidermal growth factor receptor 2 (HER2) is a member of the human epidermal growth factor receptor kinases (other members include EGFR or HER1, HER3, and HER4) that are involved in signaling cascades for cell growth and differentiation. It is well established that HER2-mediated heterodimeriza...

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Détails bibliographiques
Auteurs principaux: Banappagari, Sashikanth, Ronald, Sharon, Satyanarayanajois, Seetharama D.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005560/
https://ncbi.nlm.nih.gov/pubmed/20919746
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