Peptides containing a consensus Ras binding sequence from Raf-1 and theGTPase activating protein NF1 inhibit Ras function.

A key event in Ras-mediated signal transduction and transformation involves Ras interaction with its downstream effector targets. Although substantial evidence has established that the Raf-1 serine/threonine kinase is a critical effector of Ras function, there is increasing evidence that Ras functio...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Clark, G J, Drugan, J K, Terrell, R S, Bradham, C, Der, C J, Bell, R M, Campbell, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39983/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643674/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.4.1577
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