Peptides containing a consensus Ras binding sequence from Raf-1 and theGTPase activating protein NF1 inhibit Ras function.

Lignende værker

• RAS Signaling in Colorectal Carcinomas through Alteration of RAS, RAF, NF1, and/or RASSF1A
  af: Ahlquist, Terje, et al.
  Udgivet: (2008)
• The role of Gln61 and Glu63 of Ras GTPases in their activation by NF1 and Ras GAP.
  af: Nur-E-Kamal, M S, et al.
  Udgivet: (1992)
• The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site.
  af: Mott, H R, et al.
  Udgivet: (1996)
• Conformation of the GTPase Ras in the Membrane Affects Nanoscale Clustering and Raf Kinase Recruitment♦: The Efficacy of Raf Kinase Recruitment to the GTPase H-ras Depends on H-ras Membrane Conformer-specific Nanoclustering
  Udgivet: (2014)
• Ras-Mediated Activation of the Raf Family Kinases
  af: Terrell, Elizabeth M., et al.
  Udgivet: (2019)