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The Small GTP-binding Protein R-Ras Can Influence Integrin Activation by Antagonizing a Ras/Raf-initiated Integrin Suppression Pathway

The rapid modulation of ligand-binding affinity (“activation”) is a central property of the integrin family of cell adhesion receptors. The small GTP-binding protein Ras and its downstream effector kinase Raf-1 suppress integrin activation. In this study we explored the relationship between Ras and...

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Bibliografiske detaljer
Main Authors: Sethi, Tariq, Ginsberg, Mark H., Downward, Julian, Hughes, Paul E.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC25373/
https://ncbi.nlm.nih.gov/pubmed/10359597
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