Study of Marine Natural Products Including Resorcyclic Acid Lactones from Humicola fuscoatra That Reactivate Latent HIV-1 Expression in an in Vitro Model of Central Memory CD4+ T Cells

[Image: see text] An extract of Humicola fuscoatra (UCSC strain no. 108111A) was shown to reactivate latent HIV-1 expression in an in vitro model of central memory CD4+ T cells. We report the bioassay-guided isolation and structure determination of several resorcyclic acid lactones, including four k...

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Autori principali: Mejia, Eric J., Loveridge, Steven T., Stepan, George, Tsai, Angela, Jones, Gregg S., Barnes, Tiffany, White, Kimberly N., Drašković, Marija, Tenney, Karen, Tsiang, Manuel, Geleziunas, Romas, Cihlar, Tomas, Pagratis, Nikos, Tian, Yang, Yu, Helen, Crews, Phillip
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society and American Society of Pharmacognosy 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993908/
https://ncbi.nlm.nih.gov/pubmed/24495105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np400889x
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